NMN IS VITAL FOR OPTIMIZING NAD+ LEVELS. YOU DESERVE THE BEST.
The Role of NAD+ (Nicotinamide Adenine Dinucleotide)
NMN is an NAD+ precursor in that it restores NAD+ (an essential coenzyme) back to optimal levels. NAD+ is required for all cellular functions including life, health, and vitality. Humans cannot live without NAD+. However, NAD+ levels decline at a rate of 1% per year so that by the time we are 50 years old, our NAD+ levels are about half of what they were in our twenties. When we reach our 70’s and 80’s our NAD+ levels are drastically lower. However, clinical trials positively suggest that supplementing with NMN can boost NAD+ to youthful levels protecting us against age related deterioration and disease.
Dedication To Excellence
Certificate of Analysis: 3rd Party Testing
Gold Standard of NMN: NextGen Vitality is the Purest, Most Stabilized, Pharmaceutical Grade NMN available on the planet. Our NMN is sourced from a leading biotech manufacturer working in affiliation with the world famous nutritional, pharmaceutical, and consumer health giant GlaxoSmithKline. Every batch is Independently Third-Party Tested in a U.S. Laboratory to Ensure the Highest Purity Available. We test for (heavy metals, purity & potency, mold, yeast, fungi, and bacteria).
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The Finest, Purest, Most Stable, and Absorbable NMN on the Planet
NextGen Vitality NMN is the Most Advanced 3rd Generation NMN today. Our 3rd generation NMN resists moisture and is formulated to be stable at ambient room temperature for up to two years without loss of Potency or Degradation of Quality. NextGen Vitality’s NMN Strictly Complies with Quality Control Standards Established by U.S. Pharmacopoeia (USP is an internationally recognized agency that establishes standards for pharmaceutical development and manufacturing).
Manufactured in a GMP & NSF Certified Facility
An October 2021 industry report showed that less than 64% of NMN brands either failed to contain any NMN or fell below the amount claimed on the label.
Our NMN is manufactured in a GMP and NSF certified facility. GMP is a system for ensuring that products are consistently produced and controlled according to quality standards. NSF certification is your key to making sure that the products you use meet strict standards for public health protection.
NextGen Vitality NMN is Lactose-Free, Gluten-Free, Soy Free, Non-GMO, and Vegan.
Enhanced Absorption
Enhanced Absorption: NextGen Vitality NMN facilitates optimal bioavailability of NMN at at Slc12a8 transporter sites. Slc12a8 is an enzyme located on cell membranes in the in the small intestine. This enzyme enables NMN to bypass digestion in the liver by facilitating maximum absorption when NMN is consumed orally.
The Slc12a8 enzyme is specific to NMN and becomes activated when NAD+ levels drop. Studies have found that uptake of NMN is increased by as much as 100 times by the Slc12a8 carrier system. Heightened activation of Slc12a8 in response to falling levels of NMN adds further support to how critically important NMN and NAD+ are to living systems.
Health promoting benefits of nmn
Healthy Aging
NMN may increase the ability to fight off free radicals and oxidative stress.
NMN is the ideal supplement that can make you look and feel young again by improving skin elasticity resulting in fewer wrinkles. New research published (June 2021) shows that NMN may protect and even reverse skin damage caused by UV rays. Research has also found that NAD+ stimulates the production of collagen.
NMN may also improve bone density, eye health, and insulin sensitivity, based on age-associated studies with mice.
Naturally Derived
NMN is an entirely natural compound that can dramatically improve health and longevity. NMN occurs in all life forms including plants and animals as well as humans. It is derived from niacin, a form of vitamin B3, produced naturally within our bodies.
NMN is the precursor to the coenzyme NAD+ which is one of the most important molecules on the planet. Without NAD+ all life would cease to exist.
DNA Repair & Metabolism
Increased NAD+ levels stimulate the activity of sirtuins which promote metabolism and the speedy breakdown of food into energy which may aid in weight management. Optimized NAD+ levels stimulating metabolic activity may also shorten recovery time and prolong youth by accelerating the repair of damaged DNA.
Emerging research from clinical trials also appears to show that increasing NAD+ levels improves insulin sensitivity, increases glucose tolerance, and may help make it easier to lose weight.
Enhanced Energy
Low NAD+ levels in the body result in feeling tired and lethargic. Supplementing with NMN increases energy giving you the needed boost to propel you through the day by reducing fatigue.
NAD+ optimizes energy production and efficiency in mitochondria restoring overall vitality. Peak performance athletes seeking increased muscle strength and endurance value NMN's ability to enhance their competitive edge naturally.
Harvard mice studies show that NMN optimizes the capacity of endothelial cells lining blood vessels resulting in 80% better exercise capacity. This may also enhance mobility for people who can no longer exercise because of frailty, disability, or old age.
Healthy Heart & Brain Function
Harvard studies of aged mice suggest that boosting NAD+ levels with NMN may promote cardiovascular health by increasing the efficiency of mitochondrial energy production on an intracellular level within cardiac muscle.
These studies also suggest that elevating NAD+ levels activate SIRT1 enzymes which stimulate endothelial cells to regenerate capillaries improving blood flow and cardiovascular function.
Increased blood flow is also thought to improve cognitive function by washing away harmful waste products (metabolites) thereby supplying the brain with a robust supply of oxygen and nutrients.
Improved Sleep
NAD+ plays a critical role in the regulation of circadian rhythms keeping our sleep-wake cycles on track and in sync. As a result, NAD+ powerfully influences important physiological processes that also control metabolism.
Metabolic activities and circadian rhythms fueled by NAD+ provide an important communication link with energy-producing mitochondria throughout every cell within the body. Age-related decline in NAD+ is one reason why sleep is more restless and less restorative as we age.
Therefore, low levels of NAD+ combined with lack of sleep negatively impact our brain, heart, and overall health.
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The Hallmarks of Aging
Decreased levels of NAD+ have been associated with the hallmarks of aging. The hallmarks of aging can be thought of as mechanisms that underlie a broad range of age-related diseases. Emerging evidence implies that elevating NAD+ levels may prevent, delay, or even reverse the progression of age-related diseases.
Longevity research demonstrates that the overall common denominator of aging is an accumulation of DNA damage. This has been shown across species, from yeast to mice and humans. Current scientific research, therefore, suggests that there is a universal mechanism regulating aging which can be improved by increasing NAD+ levels.
Not surprisingly, species-specific studies have shown that elevating NAD+ levels through the use of NMN may prevent the expression of genes that cause aging by enhancing the activation of so-called "longevity-genes"known as sirtuins. Sirtuins activated by NAD+ facilitate the repair of broken DNA strands. Therefore, supplementing with NMN to boost NAD+ levels represents a potential strategy to slow or reverse aging and improve age-related conditions or diseases.
