The Collaborative Computational Project for electron cryo-microscopy (CCP-EM) supports users and developers in biological EM. The three principal aims are:

• Build a UK community for computational aspects of cryo-EM. Provide a focus for the cryo-EM community to interact with CCP4/CCPBioSim/CCPN, and the broader international community.
• Support the users of software for cryo-EM through dissemination of information on available software, and directed training.
• Support for software developers including porting, testing, and distribution of software.

CCP-EM has been supported by the MRC since 2012 through a series of Partnership Grants.

There is a mailing list for CCP-EM (supported by JISCMail). The home page for the list is at https://www.jiscmail.ac.uk/CCPEM. To subscribe to the list, click on "Subscribe or Unsubscribe" on this page. Once you have an account, you can manage your list preference from this page. You can also search the CCP-EM archive from here. Note that you must be subscribed in order to send messages to the list, and the list is PUBLIC, meaning that the archives can be accessed by anyone, and are indexed by search engines. For more details, see the JISCmail Service Policies page.

Follow us on Twitter @ccp_em.

Email us at ccpem@stfc.ac.uk.

Support for collaborative software development projects.

CCP-EM are keen to support small collaborative software development projects that are of benefit to the wider community and which produce or improve software that can be distributed through the CCP-EM software suite. We can potentially fund / co-fund developer effort in your institution using income arising from licensing of the suite to for-profit organisations. Projects are typically 3 to 6 months in duration, or longer if co-funding is available. We may be able to support studentships or events, provided there is a tangible benefit to the CCP-EM community. To find out more, please contact us at ccpem@stfc.ac.uk

News

CCP-EM software suite v1.6 is now available! See Downloads page.

Keitaro Yamashita, Colin M. Palmer, Tom Burnley and Garib N. Murshudov (2021) “Cryo-EM single-particle structure refinement and map calculation using Servalcat”, Acta Cryst D77, 1282-1291. https://doi.org/10.1107/S2059798321009475

Mateusz Olek and Agnel Praveen Joseph (2021) “Cryo-EM map based model validation using the False Discovery Rate approach”, Front. Mol. Biosci. https://doi.org/10.3389/fmolb.2021.652530

The Spring Symposium lectures are available on YouTube.

We are pleased to announce that Neil Ranson (Leeds) has taken over as the second Chair of CCP-EM. Maya Topf (Heinrich Pette Institute, Hamburg) is the new Deputy Chair.

Main references

Recent developments in the CCP-EM software suite T. Burnley, C.M. Palmer and M.D Winn, Acta Cryst., D73, 469 - 477 (2017)

Collaborative Computational Project for Electron cryo-Microscopy C. Wood, T. Burnley, A. Patwardhan, S. Scheres, M. Topf, A. Roseman and M.D Winn, Acta Cryst., D71, 123 - 126 (2015)